Temporal association of antimicrobial use in livestock with antimicrobial resistance in non-typhoid Salmonella human infections in the Netherlands, 2008-2019.

ABSTRACT:

Background

Antimicrobial use (AMU) in livestock contributes to antimicrobial resistance (AMR) among zoonotic pathogens, such as non-typhoid Salmonella (NTS). Since 2009, the Netherlands has made substantial efforts to reduce AMU in livestock.

Objectives

To assess the association between AMU in livestock and AMR in NTS human isolates. Additionally, associations between AMU in broilers/pigs and AMR in NTS broiler/pig isolates, and between AMR in broilers/pigs and in human NTS isolates were assessed. The focus was on Salmonella Enteritidis (SE) and Salmonella Typhimurium including its monophasic variant (ST/STM).

Methods

A national population registry-based study was conducted in the Netherlands from 2008 to 2019. Multivariable logistic regression mo

SUBMITTER: Chaname Pinedo LE 

PROVIDER: S-EPMC11254175 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature