An MRI radiomics approach to discriminate hemorrhage prone intracranial tumors before stereotactic biopsy.

ABSTRACT:

Purpose

To explore imaging biomarkers predictive of intratumoral hemorrhage for lesions intended for elective stereotactic biopsy.

Method

This study included a retrospective cohort of 143 patients with 175 intracranial lesions intended for stereotactic biopsy. All the lesions were randomly split into a training dataset (n=121) and a test dataset (n=54) at a ratio of 7:3. 34 lesions were defined as "hemorrhage-prone tumors" as hemorrhage occurred between initial diagnostic MRI acquisition and the scheduled biopsy procedure. Radiomics features were extracted from the contrast-enhanced T1WI and T2WI images. Features informative of hemorrhage were then selected by the LASSO algorithm and an SVM model was built with selected features. The SVM model was further simplified by disca

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11254189 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature