Association between plasma circulating tumor DNA and the prognosis of esophageal cancer patients: a meta-analysis.

ABSTRACT:

Background

The application of liquid biopsy analysis utilizing circulating tumor DNA (ctDNA) has gained prominence as a biomarker in specific cancer types. Nevertheless, the correlation between ctDNA and the prognostic outcomes of patients with esophageal cancer (EC) remains a subject of controversy. This meta-analysis aims to assess the correlation between ctDNA and the prognosis of EC patients.

Methods

We systematically explored Embase, PubMed, and the Cochrane Database to identify studies reporting on the prognostic value of ctDNA in EC patients before November 2023. The primary outcome involved the determine of associations between ctDNA with overall survival (OS), disease-free survival (DFS)/recurrence-free survival (RFS), as well asprogression-free survival (PFS) among

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11254190 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature