Impact of deep brain stimulation on urogenital function in Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Deep Brain Stimulation (DBS) effectively treats Parkinson's motor symptoms, but its effects on the urogenital system are debated.

Methods

A research was conducted in PubMed, Embase, Cochrane Library, Web of Science, and Scopus until February 27, 2024. We primarily focused on DBS's impact on Parkinson's patients' Urine storage function, voiding function, sexual function, and quality of life.

Results

Our meta-analysis included 14 studies. The main results showed that DBS resulted in fewer instances of urinary urgency (OR = 1.85, 95% CI: 1.26 to 2.70, p = 0.002) and increased maximum bladder capacity (MD = -66.10, 95% CI: -119.37 to -12.82, p = 0.02) in terms of urinary storage function. However, there were no significant differences in first des

SUBMITTER: Gao L 

PROVIDER: S-EPMC11254620 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature