Phytochemical characterization of Thevetia peruviana (lucky nut) bark extracts by GC-MS analysis, along with evaluation of its biological activities, and molecular docking study.

ABSTRACT: Thevetia peruviana (T. peruviana; Family: Apocynaceae), commonly known as Lucky Nut, is a traditionally and medicinally important plant, and the barks of the plant are traditionally used as anti-inflammatory, anti-diabetic, and antibacterial remedies. Thus, this study aimed to evaluate bioactive phytochemicals and in-vitro biological activities from the bark of T. peruviana using methanolic (TPM) and dichloromethane (TPD) extracts. The GC-MS analysis showed the presence of 54 and 39 bioactive compounds in TPM and TPD, respectively. The TPM extract has a higher level of total polyphenolic contents (TPC: 70.89 ± 1.08 and 51.07 ± 0.78 mg GAE/g extracts, while TFC: 56.89 ± 1.16 and 44.12 ± 1.76 Qu.E/g extracts for TPM and TPD, respectively). Herein, the results of antioxidant activities

SUBMITTER: Rehman Khan RA 

PROVIDER: S-EPMC11255453 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature