Zinc status in cystic fibrosis patients; a systematic review and meta-analysis.

ABSTRACT:

Background

Cystic fibrosis (CF) is an autosomal recessive hereditary disease causes concentration of secretions and this affects the lungs and digestive system. These patients are exposed to zinc (zn) deficiency. In this review, we decided to investigate the status of zn in CF patients compared to control group. Also, the clinical trials that have so far performed zinc supplementation in these patients are examined.

Method

ISI Web of Science, Scopus, PubMed/Medline, and Cochrane database were searched, up to December 2023, for studies that reported the association between zn levels of CF patients compared to a healthy control group. A random-effect model was used to compute the pooled weighted mean difference (WMD) with 95 % confidence intervals (CI). Subgroup analysis was d

SUBMITTER: Malekahmadi M 

PROVIDER: S-EPMC11255513 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature