Dietary magnesium supplementation in cats with chronic kidney disease: A prospective double-blind randomized controlled trial.

ABSTRACT:

Background

Plasma total magnesium concentration (tMg) is a prognostic indicator in cats with chronic kidney disease (CKD), shorter survival time being associated with hypomagnesemia. Whether this risk factor is modifiable with dietary magnesium supplementation remains unexplored.

Objectives

Evaluate effects of a magnesium-enriched phosphate-restricted diet (PRD) on CKD-mineral bone disorder (CKD-MBD) variables.

Animals

Sixty euthyroid client-owned cats with azotemic CKD, with 27 and 33 allocated to magnesium-enriched PRD or control PRD, respectively.

Methods

Prospective double-blind, parallel-group randomized trial. Cats with CKD, stabilized on a PRD, without hypermagnesemia (tMg >2.43 mg/dL) or hypercalcemia (plasma ionized calcium concentration, (iCa) >6 mg/d

SUBMITTER: Tang PK 

PROVIDER: S-EPMC11256178 | biostudies-literature | 2024 Jul-Aug

REPOSITORIES: biostudies-literature