Assessment of the nociceptive response to the use of cannabidiol alone and in combination with meloxicam through infrared pupillometry in female dogs undergoing elective ovariohysterectomy.

ABSTRACT: The negative effects of pain are a constant concern in the surgical management of animals, leading to the search for new drugs or more effective analgesic protocols to control this negative emotion. This study aimed to evaluate the nociceptive response of cannabidiol (CBD) alone and in combination with meloxicam using infrared pupillometry in female dogs undergoing elective ovariohysterectomy (OVH) under isoflurane anesthesia. A total of 60 female dogs of different breeds were included. These dogs were randomly assigned to four study groups according to the treatment: Control Group (G₀: n = 15) receiving saline solution; group premedicated with meloxicam at a dose of 0.2 mg Kg^-1 IV (G_Melox: n = 15). Postoperatively this drug was used at 0.1 mg

SUBMITTER: Casas-Alvarado A 

PROVIDER: S-EPMC11256235 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature