Stable high-sensitivity cardiac troponin T levels and the association with frailty and prognosis in patients with chest pain.

ABSTRACT:

Background

Chronic myocardial injury is defined by stable high-sensitivity cardiac troponin (hs-cTn) levels above the 99th percentile value, which may be a sign of a biologically aged heart. This study investigated the association between frailty and chronic myocardial injury.

Methods

In a cohort of patients with chest pain and stable hs-cTnT levels measured 2011-2014, we included all patients who were assessed by two scoring systems measuring frailty. Adjusted odds ratios (ORs) were calculated to estimate the risk of frailty at different hs-cTnT levels (referent: hs-cTnT ≤ 14 ng/l). Cox regression was used to estimate risks of death and cardiovascular events in relation to frailty status and hs-cTnT levels (referent: non-frail and hs-cTnT ≤ 14 ng/l).

Results

A total

SUBMITTER: Strandberg LS 

PROVIDER: S-EPMC11256254 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature