Gut microbiome in endometriosis: a cohort study on 1000 individuals.

ABSTRACT:

Background

Endometriosis, defined as the presence of endometrial-like tissue outside of the uterus, is one of the most prevalent gynecological disorders. Although different theories have been proposed, its pathogenesis is not clear. Novel studies indicate that the gut microbiome may be involved in the etiology of endometriosis; nevertheless, the connection between microbes, their dysbiosis, and the development of endometriosis is understudied. This case-control study analyzed the gut microbiome in women with and without endometriosis to identify microbial targets involved in the disease.

Methods

A subsample of 1000 women from the Estonian Microbiome cohort, including 136 women with endometriosis and 864 control women, was analyzed. Microbial composition was determined by sho

SUBMITTER: Perez-Prieto I 

PROVIDER: S-EPMC11256574 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature