A study protocol for risk stratification in children with concussion (RSiCC): Theoretical framework, design, and methods.

ABSTRACT: Research shows that one in five children will experience a concussion by age 16. Compared to adults, children experience longer and more severe postconcussive symptoms (PCS), with severity and duration varying considerably among children and complicating management of these patients. Persistent PCS can result in increased school absenteeism, social isolation, and psychological distress. Although early PCS diagnosis and access to evidence-based interventions are strongly linked to positive health and academic outcomes, symptom severity and duration are not fully explained by acute post-injury symptoms. Prior research has focused on the role of neuroinflammation in mediating PCS and associated fatigue; however relationship between inflammatory biomarkers and PCS severity, has not examined lo

SUBMITTER: Reuter-Rice K 

PROVIDER: S-EPMC11257289 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature