Application of untargeted liquid chromatography-mass spectrometry to routine analysis of food using three-dimensional bucketing and machine learning.

ABSTRACT: For the detection of food adulteration, sensitive and reproducible analytical methods are required. Liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) is a highly sensitive method that can be used to obtain analytical fingerprints consisting of a variety of different components. Since the comparability of measurements carried out with different devices and at different times is not given, specific adulterants are usually detected in targeted analyses instead of analyzing the entire fingerprint. However, this comprehensive analysis is desirable in order to stay ahead in the race against food fraudsters, who are constantly adapting their adulterations to the latest state of the art in analytics. We have developed and optimized an approach that enables the separate p

SUBMITTER: Hansen J 

PROVIDER: S-EPMC11258308 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature