Systematic exploration of therapeutic effects and key mechanisms of Panax ginseng using network-based approaches.

ABSTRACT:

Background

Network pharmacology has emerged as a powerful tool to understand the therapeutic effects and mechanisms of natural products. However, there is a lack of comprehensive evaluations of network-based approaches for natural products on identifying therapeutic effects and key mechanisms.

Purpose

We systematically explore the capabilities of network-based approaches on natural products, using Panax ginseng as a case study. P. ginseng is a widely used herb with a variety of therapeutic benefits, but its active ingredients and mechanisms of action on chronic diseases are not yet fully understood.

Methods

Our study compiled and constructed a network focusing on P. ginseng by collecting and integrating data on ingredients, protein targets, and kn

SUBMITTER: Kim YW 

PROVIDER: S-EPMC11258513 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature