Catalyst Editing via Post-Synthetic Functionalization by Phosphonium Generation and Anion Exchange for Nickel-Catalyzed Ethylene/Acrylate Copolymerization.

ABSTRACT: Rapid, efficient development of homogeneous catalysts featuring desired performance is critical to numerous catalytic transformations but remains a key challenge. Typically, this task relies heavily on ligand design that is often based on trial and error. Herein, we demonstrate a "catalyst editing" strategy in Ni-catalyzed ethylene/acrylate copolymerization. Specifically, alkylation of a pendant phosphine followed by anion exchange provides a high yield strategy for a large number of cationic Ni phosphonium catalysts with varying electronic and steric profiles. These catalysts are highly active in ethylene/acrylate copolymerization, and their behaviors are correlated with the electrophile and the anion used in late-stage functionalization.

SUBMITTER: Ghana P 

PROVIDER: S-EPMC11258788 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature