Cardiometabolic Characteristics of Obesity Phenotypes in Persons With HIV.

ABSTRACT:

Background

In the general population, it is established that adipose tissue depots pose various risks for cardiometabolic diseases. The interaction among obesity, HIV, and antiretroviral treatment promotes even greater risk for persons with HIV (PWH). As obesity is a heterogeneous condition, determining the specific obesity phenotypes present and their characteristics is critical to personalize care in PWH.

Methods

Visceral, sarcopenic, myosteatotic, hepatosteatotic, and metabolically healthy obesity phenotypes were determined by pre-established cut points after segmentation of computed tomography scans at the L3 vertebra. Multivariable linear regression modeling included anthropometrics, clinical biomarkers, and inflammatory factors while controlling for age, sex, race, and

SUBMITTER: Swartz AZ 

PROVIDER: S-EPMC11259191 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature