Validating the performance of organ dysfunction scores in children with infection: A cohort study.

ABSTRACT:

Purpose

We aimed to validate the performance of six available scoring models for predicting hospital mortality in children with suspected or confirmed infections.

Methods

This single-center retrospective cohort study included pediatric patients admitted to the PICU for infection. The primary outcome was hospital mortality. The six scores included the age-adapted pSOFA score, SIRS score, PELOD2 score, Sepsis-2 score, qSOFA score, and PMODS.

Results

Of the 5,356 children admitted to the PICU, 9.1% (488) died, and 25.1% (1,342) had basic disease with a mortality rate of 12.7% (171); 65.3% (3,499) of the patients were younger than 2 years, and 59.4% (3,183) were male. The discrimination abilities of the pSOFA and PELOD2 scores were superior to those of the other models. T

SUBMITTER: Li S 

PROVIDER: S-EPMC11259267 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature