Extensively Drug-Resistant Pseudomonas aeruginosa Outbreak Associated With Artificial Tears.

ABSTRACT:

Background

Carbapenemase-producing, carbapenem-resistant Pseudomonas aeruginosa (CP-CRPA) are extensively drug-resistant bacteria. We investigated the source of a multistate CP-CRPA outbreak.

Methods

Cases were defined as a US patient's first isolation of P. aeruginosa sequence type 1203 with carbapenemase gene blaVIM-80 and cephalosporinase gene blaGES-9 from any specimen source collected and reported to the Centers for Disease Control and Prevention during 1 January 2022-15 May 2023. We conducted a 1:1 matched case-control study at the post-acute care facility with the most cases, assessed exposures associated with case status for all case-patients, and tested products for bacterial contamination.

Results

We identified 81 case-patients from 18 states, 27 of whom wer

SUBMITTER: Grossman MK 

PROVIDER: S-EPMC11259536 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature