Identification of homer protein homolog 3 as a prognostic marker of colon adenocarcinoma.

ABSTRACT:

Background

Homer protein homolog 3 (HOMER3), a factor implicated in both physiological and pathological processes, has been studied extensively to determine the relationship between its expression level and the prognosis of various malignancies. However, the significance and clinicopathological role of HOMER3 in colorectal adenocarcinoma remain unclear.

Methods

In this study, bioinformatics techniques were used to find the correlation between high HOMER3 expression levels and clinicopathological features of colorectal adenocarcinoma (COAD) patients.

Results

Cellular experiments confirmed the differential expression of HOMER3 in tumor cells compared to normal cells. HOMER3 overexpression was significantly associated with COAD staging

SUBMITTER: Luo M 

PROVIDER: S-EPMC11259827 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature