Human metapneumovirus infection is associated with a substantial morbidity and mortality burden in adult inpatients.

ABSTRACT:

Background

Human metapneumovirus (hMPV) is one of the leading respiratory viruses. This prospective observational study aimed to describe the clinical features and the outcomes of hMPV-associated lower respiratory tract infections in adult inpatients.

Methods

Consecutive adult patients admitted to one of the 31 participating centers with an acute lower respiratory tract infection and a respiratory multiplex PCR positive for hMPV were included. A primary composite end point of complicated course (hospital death and/or the need for invasive mechanical ventilation) was used.

Results

Between March 2018 and May 2019, 208 patients were included. The median age was 74 [62-84] years. Ninety-seven (47 %) patients were men, 187 (90 %) had at least one coexisting illness, and 67

SUBMITTER: Philippot Q 

PROVIDER: S-EPMC11259828 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature