Fecal Immunochemical Test Screening and Risk of Colorectal Cancer Death.

ABSTRACT:

Importance

The fecal immunochemical test (FIT) is widely used for colorectal cancer (CRC) screening, but evidence of its effectiveness is limited.

Objective

To evaluate whether FIT screening is associated with a lower risk of dying from CRC overall, according to cancer location, and within demographic groups.

Design, setting, and participants

This nested case-control study in a cohort of screening-eligible people was conducted in 2 large, integrated health systems of racially, ethnically, and socioeconomically diverse members with long-term programs of mailed FIT screening outreach. Eligible participants included people aged 52 to 85 years who died from colorectal adenocarcinoma between 2011 and 2017 (cases); cases were matched in a 1:8 ratio based on age, sex, health

SUBMITTER: Doubeni CA 

PROVIDER: S-EPMC11259903 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature