Completion Rate and Positive Results Reporting Among Immunotherapy Trials in Breast Cancer, 2004-2023.

ABSTRACT:

Importance

Clinical trials are the path to test and introduce new therapies in the clinic. Trials that are unable to produce results represent inefficiency in the system and may also undermine patient confidence in the new drug development process.

Objectives

To survey the immunotherapy clinical trial landscape of breast cancer between January 2004 and April 2023 and examine what fraction of trials with primary completion date up to November 30, 2022, failed to report outcome, assessing the proportion of trials that yielded positive results and describing trial features associated with these 2 outcomes.

Design, setting, and participants

This cross-sectional study included breast cancer immunotherapy trials identified in ClinicalTrials.gov. Trial details and results we

SUBMITTER: Mariani M 

PROVIDER: S-EPMC11259908 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature