Association between preoperative white blood cell counts and thirty-day surgical mortality after craniotomy in adult intracranial tumor patients.

ABSTRACT:

Objective

White blood cell (WBC) counts has been identified as a prognostic biomarker which frequently predict adverse outcomes and mortality risk in various conditions. However, evidence for the association between WBC counts and short-term outcomes after intracranial tumor resection remains limited. This study aimed to explore associations between preoperative WBC counts and thirty-day surgical mortality after craniotomy in adult intracranial tumor patients.

Methods

This retrospective cohort study performed secondary analysis of 18,049 intracranial tumor craniotomy patients from the ACS NSQIP database (2012-2015). The major exposure and outcome were preoperative WBC counts and thirty-day surgical mortality, respectively. Cox regression modeling assessed the linear associat

SUBMITTER: Gao Z 

PROVIDER: S-EPMC11259970 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature