Heparin-induced thrombocytopenia after cardiac surgery. A single-center, retrospective cohort study.

ABSTRACT:

Background

Cardiac surgery is a high-risk setting for heparin-induced thrombocytopenia (HIT). However, large differences in its incidence, rate of thrombotic complications, and mortality have been reported in this context. Few studies address the pharmacologic management of HIT specifically in this setting.

Objectives

To describe the incidence, outcomes, and management of patients with HIT in our cohort and to compare them with patients presenting platelet factor 4/heparin antibodies but without platelet-activating capacity.

Methods

A retrospective observational study was conducted over a period of 10 years and 6 months on 13,178 cardiac operations in a single high-volume cardiac surgery center.

Results

HIT was diagnosed in 0.22% of patients. HIT with associate

SUBMITTER: Bevilacqua S 

PROVIDER: S-EPMC11260323 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature