Secondary Malignancies in Multiple Myeloma in Korean Patients: A Nationwide Population-Based Study.

ABSTRACT:

Purpose

This study investigated the incidence of secondary malignancy in multiple myeloma (MM) patients compared with that in the general population using a population-based database covering all residents in Korea.

Materials and methods

Based on the national health insurance system in Korea, all people primarily diagnosed with MM between January 1, 2010 to December 31, 2018 were identified. A total of 9,985 MM patients aged ≥ 20 years in Korea were included.

Results

Among them, 237 (2.4%) developed secondary malignancies by 2018. The standardized incidence rates (SIRs) of all secondary malignancies in MM patients were 0.87 (95% confidence interval [CI], 0.76 to 0.98), with a higher incidence of hematologic malignancies than in the general population with an SIR of 3.

SUBMITTER: Park B 

PROVIDER: S-EPMC11261182 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature