Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment.

ABSTRACT:

Background/aims

Quick sequential organ failure assessment (qSOFA) is believed to identify patients at risk of poor outcomes in those with suspected infection. We aimed to evaluate the ability of modified qSOFA (m-qSOFA) to identify high-risk patients among those with acutely deteriorated chronic liver disease (CLD), especially those with acute-onchronic liver failure (ACLF).

Methods

We used data from both the Korean Acute-on-Chronic Liver Failure (KACLiF) and the Asian Pacific Association for the Study of the Liver ACLF Research Consortium (AARC) cohorts. qSOFA was modified by replacing the Glasgow Coma Scale with hepatic encephalopathy, and an m-qSOFA ≥2 was considered high.

Results

Patients with high m-qSOFA had a significantly lower 1-month transplant-free survival

SUBMITTER: Song DS 

PROVIDER: S-EPMC11261223 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature