Brain functional gradient and structure features in adolescent and adult autism spectrum disorders.

ABSTRACT: Understanding how function and structure are organized and their coupling with clinical traits in individuals with autism spectrum disorder (ASD) is a primary goal in network neuroscience research for ASD. Atypical brain functional networks and structures in individuals with ASD have been reported, but whether these associations show heterogeneous hierarchy modeling in adolescents and adults with ASD remains to be clarified. In this study, 176 adolescent and 74 adult participants with ASD without medication or comorbidities and sex, age matched healthy controls (HCs) from 19 research groups from the openly shared Autism Brain Imaging Data Exchange II database were included. To investigate the relationship between the functional gradient, structural changes, and clinical symptoms of brain n

SUBMITTER: Ruan L 

PROVIDER: S-EPMC11261594 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature