FET PET provides adjunctive value to FDG PET in distinction of spinal cord tumors.

ABSTRACT:

Objective

This study aimed to compare the diagnostic efficacy of O-(2-¹⁸F-fluoroethyl)-l-tyrosine (¹⁸F-FET) PET and 2-deoxy-2-[¹⁸F]fluoro-d-deoxyglucose (¹⁸F-FDG) PET for spinal cord lesions.

Materials and methods

Paired preoperative ¹⁸F-FDG PET/MRI and ¹⁸F-FET PET/MRI scans were conducted on patients with suspected spinal cord tumors. Clinical manifestations and PET performance, including SUVmean, SUVmax, TBRmean, TBRmax, metabolic tumor volume (MTV), and total lesion metabolism (TLM), and tumor volume, were compared using group analysis and receiver operating characteristic (ROC) curves.

Results

Thirty-five patients were categorized into three groups based on their pathological diagnosis: high-grade t

SUBMITTER: Liu P 

PROVIDER: S-EPMC11261781 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature