Longitudinal gut microbial signals are associated with weight loss: insights from a digital therapeutics program.

ABSTRACT:

Introduction

The gut microbiome's influence on weight management has gained significant interest for its potential to support better obesity therapeutics. Patient stratification leading to personalized nutritional intervention has shown benefits over one-size-fit-all diets. However, the efficacy and impact on the gut's microbiome of personalizing weight loss diets based on individual factors remains under-investigated.

Methods

This study assessed the impact of Digbi Health's personalized dietary and lifestyle program on weight loss and the gut microbiome end-points in 103 individuals. Participants' weight loss patterns and gut microbiome profiles were analyzed from baseline to follow-up samples.

Results

Specific microbial genera, functional pathways, and communities a

SUBMITTER: Kumbhare SV 

PROVIDER: S-EPMC11262244 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature