Development and Validation of a Machine Learning COVID-19 Veteran (COVet) Deterioration Risk Score.

ABSTRACT:

Background and objective

To develop the COVid Veteran (COVet) score for clinical deterioration in Veterans hospitalized with COVID-19 and further validate this model in both Veteran and non-Veteran samples. No such score has been derived and validated while incorporating a Veteran sample.

Derivation cohort

Adults (age ≥ 18 yr) hospitalized outside the ICU with a diagnosis of COVID-19 for model development to the Veterans Health Administration (VHA) (n = 80 hospitals).

Validation cohort

External validation occurred in a VHA cohort of 34 hospitals, as well as six non-Veteran health systems for further external validation (n = 21 hospitals) between 2020 and 2023.

Prediction model

eXtreme Gradient Boosting machine learning methods were used, and performance was ass

SUBMITTER: Govindan S 

PROVIDER: S-EPMC11262818 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature