Neurodevelopmental outcomes of preterm with necrotizing enterocolitis: a systematic review and meta-analysis.

ABSTRACT: While neonatal necrotising enterocolitis (NEC) is associated with high mortality rates in newborns, survivors can face long-term sequelae. However, the relationship between NEC and neurodevelopmental impairment (NDI) in preterm infants remains unclear. To explore the relationship between neonatal NEC and neurodevelopmental outcomes in preterm infants, we searched PubMed, EMBASE, and the Cochrane Library from their inception to February 2024 for relevant studies. Studies included were cohort or case-control studies reporting neurodevelopmental outcomes of NEC in preterm infants. Two independent investigators extracted data regarding brain damage and neurodevelopmental outcomes in these infants at a corrected age exceeding 12 months. Odds ratios (ORs) were pooled using a random effects model

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11263237 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature