Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex.

ABSTRACT: During economic choice, options are often considered in alternation, until commitment. Nonetheless, neuroeconomics typically ignores the dynamic aspects of deliberation. We trained two male macaques to perform a value-based decision-making task in which two risky offers were presented in sequence at the opposite sides of the visual field, each followed by a delay epoch where offers were invisible. Surprisingly, during the two delays, subjects tend to look at empty locations where the offers had previously appeared, with longer fixations increasing the probability of choosing the associated offer. Spiking activity in orbitofrontal cortex reflects the value of the gazed offer, or of the offer associated with the gazed empty spatial location, even if it is not the most recent. This reactivati

SUBMITTER: Ferro D 

PROVIDER: S-EPMC11263430 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature