Structure based functional identification of an uncharacterized protein from Coxiella burnetii involved in adipogenesis.

ABSTRACT: Coxiella burnetii, the causative agent of Q fever, is an intracellular pathogen posing a significant global public health threat. There is a pressing need for dependable and effective treatments, alongside an urgency for further research into the molecular characterization of its genome. Within the genomic landscape of Coxiella burnetii, numerous hypothetical proteins remain unidentified, underscoring the necessity for in-depth study. In this study, we conducted comprehensive in silico analyses to identify and prioritize potential hypothetical protein of Coxiella burnetii, aiming to elucidate the structure and function of uncharacterized protein. Furthermore, we delved into the physicochemical properties, localization, and molecular dynamics and simulations, and assessed the primary, secon

SUBMITTER: Mamun TI 

PROVIDER: S-EPMC11263603 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature