Quality of life in patients with statin intolerance: a multicentre prospective registry study.

ABSTRACT:

Background

Statin intolerance is associated with increased cardiovascular risk. Symptoms and patients' characteristics are incompletely known. We aimed to analyse the health-related quality of life (QOL) associated with statin intolerance.

Methods

The Statin Intolerance Registry (SIR) is an observational, prospective, multicentre study that included 1111 patients, with intolerance to at least two different statins, between 2021 and 2023 in Germany. SIR baseline data were compared to individuals with and without statin therapy of the population-based LIFE-Adult Study (n = 9983).

Findings

The mean age in SIR was 66.1 years (standard deviation (SD) 9.9). The cohort was characterized by a higher proportion of women compared to patients on statins in LIFE-Adult (57.7% vs.

SUBMITTER: Sturzebecher PE 

PROVIDER: S-EPMC11263645 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature