Venous thromboembolism incidence and association with overall survival in pancreatic cancer: A Finnish nationwide cohort study.

ABSTRACT:

Introduction

Pancreatic cancer (PC) is associated with a high risk of venous thromboembolic events (VTEs). We investigated the incidence of VTE before and after the diagnosis of PC and its association with overall survival.

Methods

We identified PC patients diagnosed in 2013-2016 from the Finnish Cancer Registry. Data on healthcare visits and death were collected, along with follow-up data through the end of 2020. We compared patients who underwent radical-intent surgery (RIS) to those who underwent palliative treatment (PT) alone.

Results

We identified 4086 PC patients, of whom 343 (8.4%) underwent RIS and 3743 (91.6%) received PT. VTE incidence within 1 year before a PC diagnosis was higher in the PT (4.2%, n = 156) than in the RIS group (0.6%, n = 2; p < 0.001). Th

SUBMITTER: Aaltonen P 

PROVIDER: S-EPMC11263919 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature