Itching Frequency and Neuroanatomic Correlates in Frontotemporal Lobar Degeneration.

ABSTRACT:

Importance

Itching is common in geriatric populations and is frequently linked to dermatological or systemic conditions. Itching engages specific brain regions that are implicated in the pathogenesis of frontotemporal lobar degeneration spectrum disorders (FTLD-SD). Thus, itching of undetermined origin (IUO) may indicate the presence of a neurodegenerative process.

Objective

To compare the frequency of itching in FTLD-SD and Alzheimer disease (AD) and to determine the neuroanatomical underpinnings of IUO.

Design, setting, and participants

This case-control study evaluated data and brain magnetic resonance images (MRIs) for participants with FTLD-SD or AD. Participants of a research study on FTLD-SD at the University of California, San Francisco, Memory and Aging Cente

SUBMITTER: Hadad R 

PROVIDER: S-EPMC11264090 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature