Association between whole blood ratio and risk of mortality in massively transfused trauma patients: retrospective cohort study.

ABSTRACT:

Background

Although whole blood (WB) transfusion was reported to improve survival in trauma patients with hemorrhagic shock, little is known whether a higher proportion of WB is associated with an improved survival. This study aimed to evaluate the association between whole blood ratio (WBR) and the risk of mortality in trauma patients requiring massive blood transfusion.

Methods

We performed a retrospective cohort study from the ACS-TQIP between 2020 and 2021. Patients were aged ≥ 18 years and received WB within 4 h of hospital arrival as a part of massive blood transfusion. Study patients were categorized into four groups based on the quartiles of WBR. Primary outcome was 24-h mortality and secondary outcome was 30-day mortality. Multivariable logistic regression analysis,

SUBMITTER: Aoki M 

PROVIDER: S-EPMC11264807 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature