Microbiome in radiotherapy: an emerging approach to enhance treatment efficacy and reduce tissue injury.

ABSTRACT: Radiotherapy is a widely used cancer treatment that utilizes powerful radiation to destroy cancer cells and shrink tumors. While radiation can be beneficial, it can also harm the healthy tissues surrounding the tumor. Recent research indicates that the microbiota, the collection of microorganisms in our body, may play a role in influencing the effectiveness and side effects of radiation therapy. Studies have shown that specific species of bacteria living in the stomach can influence the immune system's response to radiation, potentially increasing the effectiveness of treatment. Additionally, the microbiota may contribute to adverse effects like radiation-induced diarrhea. A potential strategy to enhance radiotherapy outcomes and capitalize on the microbiome involves using probiotics. Prob

SUBMITTER: Lu L 

PROVIDER: S-EPMC11264922 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature