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Hypercalcaemia in gastrointestinal stromal tumour and sarcoidosis: a case report.


ABSTRACT:

Background

Hypercalcaemia is a common manifestation of sarcoidosis but is sparingly described in gastrointestinal stromal tumours (GISTs). We describe a case of acute kidney injury and hypercalcemia resulting from simultaneous diagnosis of GIST and sarcoidosis, the presentation of which has not yet been reported.

Case presentation

A 61-year-old male presented with acute kidney injury and hypercalcemia, with elevated 1,25-dihydroxyvitamin D levels. Investigations demonstrated a large gastric antral mass which was resected and proven to be GIST. Histopathology of incidentally found liver nodules revealed non-necrotising epithelioid granulomas consistent with concomitant sarcoidosis. The hypercalcemia was successfully treated with bisphosphonate therapy, resection of the GIST a

SUBMITTER: Selvananthan B 

PROVIDER: S-EPMC11264955 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature