Gut microbiota in preterm infants with late-onset sepsis and pneumonia: a pilot case-control study.

ABSTRACT:

Background

Late-onset sepsis (LOS) and pneumonia are common infectious diseases, with high morbidity and mortality in neonates. This study aimed to investigate the differences in the gut microbiota among preterm infants with LOS, or pneumonia, and full-term infants. Furthermore, this study aimed to determine whether there is a correlation between intestinal pathogenic colonization and LOS.

Methods

In a single-center case‒control study, 16 S rRNA gene sequencing technology was used to compare gut microbiota characteristics and differences among the LOS group, pneumonia group, and control group.

Results

Our study revealed that the gut microbiota in the control group was more diverse than that in the LOS group and pneumonia group (P < 0.05). No significant differences in

SUBMITTER: Ma Y 

PROVIDER: S-EPMC11265154 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature