Reappearance of founder virus sequence in human immunodeficiency virus type 1-infected patients.

ABSTRACT: Different patterns of temporal evolution in human immunodeficiency virus type 1 V3 and p17 regions are described for eight patients studied during the first years following primary infection. In samples from three patients, a rapid replacement of the major sequence occurred but the original sequence reappeared later simultaneously with clinical deterioration and increased plasma viral load.

SUBMITTER: Karlsson AC 

PROVIDER: S-EPMC112691 | biostudies-literature | 1999 Jul

REPOSITORIES: biostudies-literature