Water-filtered infrared A radiation hyperthermia combined with immunotherapy for advanced gastrointestinal tumours.

ABSTRACT: This study pioneered the use of WIRA whole-body infrared hyperthermia combined with ICI therapy to treat GIT and verified the feasibility and safety of HIT. The final results showed a DCR of 55.6%, with a median PFS of 53.5 days, median OS of 134 days, and an irAE incidence of 22.2%. Therefore, we believe that HIT can exert multiple synergistic sensitisation effects, thereby providing clinical benefits to patients with advanced GITs, increasing overall safety, and improving patients' QOL.

SUBMITTER: Liu P 

PROVIDER: S-EPMC11269209 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature