Machine learning to promote translational research: predicting patent and clinical trial inclusion in dementia research.

ABSTRACT: Projected to impact 1.6 million people in the UK by 2040 and costing £25 billion annually, dementia presents a growing challenge to society. This study, a pioneering effort to predict the translational potential of dementia research using machine learning, hopes to address the slow translation of fundamental discoveries into practical applications despite dementia's significant societal and economic impact. We used the Dimensions database to extract data from 43 091 UK dementia research publications between the years 1990 and 2023, specifically metadata (authors, publication year, etc.), concepts mentioned in the paper and the paper abstract. To prepare the data for machine learning, we applied methods such as one-hot encoding and word embeddings. We trained a CatBoost Classifier to predic

SUBMITTER: Beinat M 

PROVIDER: S-EPMC11269431 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature