Expression of Transposable Elements throughout the Fasciola hepatica Trematode Life Cycle.

ABSTRACT:

Background

Transposable elements (TEs) are major components of eukaryotic genomes. The extensive body of evidence suggests that although they were once considered "genomic parasites", transposons and their transcripts perform specific functions, such as regulation of early embryo development. Understanding the role of TEs in such parasites as trematodes is becoming critically important. Fasciola hepatica, a parasite affecting humans and livestock, undergoes a complex life cycle in diverse environments and hosts, and knowledge about its life cycle regulation is scarce so far.

Methods

We summarized the data regarding the repetitive elements in F. hepatica and conducted bulk RNA-seq analysis across its life cycle stages. TE expression profiles were analyzed, focus

SUBMITTER: Skalon EK 

PROVIDER: S-EPMC11270206 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature