Proteomics in Patients with Fibromyalgia Syndrome: A Systematic Review of Observational Studies.

ABSTRACT:

Purpose of review

Fibromyalgia syndrome (FMS) is a disease of unknown pathophysiology, with the diagnosis being based on a set of clinical criteria. Proteomic analysis can provide significant biological information for the pathophysiology of the disease but may also reveal biomarkers for diagnosis or therapeutic targets. The present systematic review aims to synthesize the evidence regarding the proteome of adult patients with FMS using data from observational studies.

Recent findings

An extensive literature search was conducted in MEDLINE/PubMed, CENTRAL, and clinicaltrials.gov from inception until November 2022. The study protocol was published in OSF. Two independent reviewers evaluated the studies and extracted data. The quality of studies was assessed using the modified

SUBMITTER: Gkouvi A 

PROVIDER: S-EPMC11271354 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature