Cortico-cortical drive in a coupled premotor-primary motor cortex dynamical system.

ABSTRACT: In the conventional view of sensorimotor control, the premotor cortex (PM) plans actions that are executed by the primary motor cortex (M1). This notion arises in part from many experiments that have imposed a preparatory "planning" period, during which PM becomes active without M1. But during many natural movements, PM and M1 are co-activated, making it difficult to distinguish their functional roles. We leverage coupled dynamical systems models (cDSMs) to uncover interactions between PM and M1 during movements performed with no preparatory period. We build cDSMs using neural and behavioral data recorded from two non-human primates as they performed a reach-grasp-manipulate task. PM and M1 interact dynamically throughout these movements. Whereas PM drives the M1 in some situations, in oth

SUBMITTER: D'Aleo R 

PROVIDER: S-EPMC11271678 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature