American Cutaneous Leishmaniasis: Imported cases in Berlin 2000-2023.

ABSTRACT:

Background

American Cutaneous Leishmaniasis (ACL) shows variable response to therapy, but data on species-specific treatment efficacy is scarce. We describe the clinical characteristics and outcome of patients with ACL imported to a tertiary centre in Germany and determine whether species-specific therapy according to the 2014 "LeishMan" group recommendations is associated with cure.

Methods

A retrospective chart review was conducted at the Charité Institute of International Health in Berlin. We analysed data on PCR-confirmed ACL cases collected between 2000 and 2023. Systemic therapy included liposomal amphotericin B, miltefosine, pentavalent antimony, ketoconazole or itraconazole. Localized therapy included perilesional pentavalent antimony or paromomycin ointment. Cure wa

SUBMITTER: Lindner AK 

PROVIDER: S-EPMC11271916 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature