Promoting equity in clinical research: The role of social determinants of health.

ABSTRACT:

Objective

This study aims to investigate the association between social determinants of health (SDoH) and clinical research recruitment outcomes and recommends evidence-based strategies to enhance equity.

Materials and methods

Data were collected from the internal clinical study manager database, clinical data warehouse, and clinical research registry. Study characteristics (e.g., study phase) and sociodemographic information were extracted. Median neighborhood income, distance from the study location, and Area Deprivation Index (ADI) were calculated. Mixed effect generalized regression was used for clustering effects and false discovery rate adjustment for multiple testing. A stratified analysis was performed to examine the impact in distinct medical departments.

Results

SUBMITTER: Idnay B 

PROVIDER: S-EPMC11272440 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature