Association between telomere length and neuropsychological function at 4-5 years in children from the INMA project: a cross-sectional study.

ABSTRACT: Shortened telomere length (TL) has been associated with lower cognitive performance, different neurological diseases in adults, and certain neurodevelopmental disorders in children. However, the evidence about the association between TL and neuropsychological developmental outcomes in children from the general population is scarce. Therefore, this study aimed to explore the association between TL and neuropsychological function in children 4-5 years of age. We included 686 children from the INMA Project, a population-based birth cohort in Spain. Leucocyte TL was determined by quantitative PCR method, and neuropsychological outcomes were measured using the McCarthy Scales of Children's Abilities (MCSA). Multiple linear regression models were used to estimate associations adjusted for potent

SUBMITTER: Campos-Sanchez I 

PROVIDER: S-EPMC11272730 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature