Bilateral Mastectomy and Breast Cancer Mortality.

ABSTRACT:

Importance

The benefit of bilateral mastectomy for women with unilateral breast cancer in terms of deaths from breast cancer has not been shown.

Objectives

To estimate the 20-year cumulative risk of breast cancer mortality among women with stage 0 to stage III unilateral breast cancer according to the type of initial surgery performed.

Design, settings, and participants

This cohort study used the Surveillance, Epidemiology, and End Results (SEER) Program registry database to identify women with unilateral breast cancer (invasive and ductal carcinoma in situ) who were diagnosed from 2000 to 2019. Three closely matched cohorts of equal size were generated using 1:1:1 matching according to surgical approach. The cohorts were followed up for 20 years for contralateral bre

SUBMITTER: Giannakeas V 

PROVIDER: S-EPMC11273285 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature