Identification of Predictive Biomarkers of Lameness in Transition Dairy Cows.

ABSTRACT: The aim of this study was to identify with a high level of confidence metabolites previously identified as predictors of lameness and understand their biological relevance by carrying out pathway analyses. For the dairy cattle sector, lameness is a major challenge with a large impact on animal welfare and farm economics. Understanding metabolic alterations during the transition period associated with lameness before the appearance of clinical signs may allow its early detection and risk prevention. The annotation with high confidence of metabolite predictors of lameness and the understanding of interactions between metabolism and immunity are crucial for a better understanding of this condition. Using liquid chromatography-tandem mass spectrometry (LC-MS/MS) with authentic standards to inc

SUBMITTER: Cardoso AS 

PROVIDER: S-EPMC11273747 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature